Quetiapine is an antipsychotic often prescribed to treat disorders such as schizophrenia and bipolar disorders. While this medication can provide significant benefits for patients, it is essential to recognize and monitor the potential side effects as well as the contraindications that accompany it. Among these adverse effects, some may prove to be more frequent in certain population groups, particularly children and adolescents. Therefore, special attention must be paid to its use.

Medical prescription of quetiapine: side effects and contraindications to know

Quetiapine is a widely used antipsychotic medication in the treatment of several psychiatric disorders, including schizophrenia and bipolar disorders. This treatment is also used in certain situations of major anxiety or depression. However, despite its therapeutic advantages, it is crucial to be aware of the side effects and contraindications that arise in order to ensure safe and effective prescribing. This detailed notice aims to describe these key aspects related to the prescription of quetiapine.

Side effects of quetiapine

Like any medication, quetiapine can cause a number of side effects. These may vary depending on the dose, duration of treatment, and individual patient sensitivity. Among the most common adverse effects, drowsiness is often reported. This can impact the ability to drive or perform tasks requiring increased alertness.

In addition to drowsiness, other side effects include:

• Dizziness: These sensations can make standing difficult, especially after a rapid change in position.
• Weight gain: This can occur due to changes in metabolism and eating habits.
• Gastrointestinal disturbances: These disturbances, including nausea or vomiting, are common when starting treatment.
• Dry mouth: Difficulty in swallowing food can cause discomfort.
• Constipation: This can be a lasting side effect requiring dietary changes.
• Neurological effects: This includes tremors, involuntary movements, or symptoms similar to Parkinson’s disease, which may require dosage adjustments.

Adverse effects do not occur in all patients and are manageable in most cases. However, in the event of severe symptoms such as chest pain, high temperature, or changes in blood composition, it is essential to consult a health professional without delay.

Contraindications to the prescription of quetiapine

Quetiapine is not appropriate for all patients. Several contraindications are important to emphasize, including:

• Lactose intolerance: This medication contains lactose, making its use inappropriate for patients intolerant to galactose or those with lactase deficiency.
• History of heart disease: Quetiapine may have side effects on heart rhythm. Patients with a history of cardiac disorders should avoid this treatment.
• Concurrent use with certain medications: Quetiapine has potential interactions with substances such as beta-blockers, which may increase the risk of cardiac complications.
• Pregnant or breastfeeding women: The effects of quetiapine on the fetus or infant are still poorly understood. Its prescription must be strictly controlled in these cases.
• Liver diseases: The excretion of the medication may be affected by altered liver function, necessitating dosage adjustments or alternative therapeutic options.

Cautions should be discussed with the health professional, who can assess the individual benefit/risk ratio for each patient.

In summary, quetiapine represents an important treatment in managing various psychiatric disorders. However, being aware of the potential side effects and contraindications is crucial to maximize treatment safety. Before starting treatment with quetiapine, a thorough consultation with a healthcare professional is strongly recommended to adjust treatment according to the individual specifics of each patient.

FAQ on the medical prescription of quetiapine

Q: What are the common side effects of quetiapine?
A: The most common side effects include drowsiness, dizziness, and gastrointestinal disturbances.

Q: Is quetiapine indicated for everyone?
A: No, quetiapine is contraindicated in individuals who have lactose intolerance or galactose deficiency.

Q: What are the main indications for quetiapine?
A: It is primarily used to treat schizophrenia and bipolar disorders, but may also be prescribed for other psychiatric disorders.

Q: What are the signs of a quetiapine overdose?
A: Signs of overdose may include excessive drowsiness, confusion, and cardiac instability.

Q: How should quetiapine be discontinued?
A: It is recommended to stop quetiapine gradually, as sudden withdrawal can cause insomnia, nausea, or headaches.

Q: What are the risks associated with prolonged treatment with quetiapine?
A: Prolonged treatment may lead to heart rhythm problems and other adverse effects, some of which may be serious.

Q: Can quetiapine interact with other medications?
A: Yes, quetiapine can interact with various medications, so it is important to consult a healthcare professional before taking other treatments simultaneously.

Q: Does quetiapine have any effects on children?
A: The effects of quetiapine on children and adolescents are not fully known, and it is generally not prescribed before the age of 18, except in absolute necessity.